Evaluating the Efficacy of Thymus vulgaris L. from the Garmian Region: Chemical Composition and Clinical Application for Stomach Bacterial Infections

Abstract

Thymus vulgaris L. (thyme) is being studied to see if it can be used as an extra treatment for Helicobacter pylori (H. pylori) illnesses. H. pylori is a gramme-negative bacteria that has been linked to both peptic sores and stomach cancer. They need to find other options because popular drugs aren't working as well as they used to. Bioactive parts of thyme, like p-cymene, carvacrol, and thymol, kill germs very well and have been used in traditional medicine for a long time. A three-week clinical study with 48 people with stomach infections compared thyme extract to a standard chemical treatment (Pylokit) that included tinidazole, clarithromycin, and lansoprazole. The thyme extract significantly lowered the number of germs, with an average drop of 5.14 units by week three. This worked better than the chemical treatment and didn't hurt anything. Chemical tests with GC-MS showed that the main antibiotic in thyme is thymol (59.99%). There is also carvacrol and p-cymene. These results suggest that thyme may be a good natural and effective way to treat H. pylori. This means that more clinical research is needed.